Abstract The majority of mutational signatures have been characterized in tumors from Western countries and the degree to which mutational signatures are similar or different in Eastern populations has not been fully explored. We leveraged a large-scale clinical sequencing cohort of tumors from a Chinese population containing 25 tumor types and found that the highly ……
Tomoki is a new postdoctoral fellow in the lab.
Raghad is a new Bioinformatics analysts in the lab.
Jingwen is a new Bioinformatics analysts in the lab.
Natasha is a new graduate students in the lab.
Amulya is a new graduate students in the lab.
Project Summary Despite their many advantages, single-cell technologies can suffer from the presence of contamination arising from different sources. High levels of contamination can hinder important analyses such as clustering, marker identification, and differential expression. This team has previously developed a tool called decontX that estimates and removes contamination arising from the presence of ambient ……
The Campbell Lab is participating in an Ancestry Seed Network within the Human Cell Atlas (HCA). This project aims to leverage state-of-the-art techniques to characterize cellular heterogeneity across ancestries and ages in the healthy prostate. This network is led by Franklin Huang at UCSF and a collaboration of investigators from UCSF, University of Texas, and Boston University.
We’re very excited to announce the publication of the musicatk toolkit which is open access at the AACR journal Cancer Research. musicatk provides a comprehensive workflow for the analysis and visualization of mutational signatures. Available on Bioconductor!
New funding from NCI – The Campbell lab has received a new U01 from the NCI’s ITCR program to develop novel methods and software for mutational signature inference in collaboration with the Yajima and Huggins labs at BU. Additionally, the lab has received a new R01 from the NCI’s Center to Reduce Cancer Health Disparities to ……