ExperimentSubset is an R package to manage subsets of Bioconductor Experiment objects. ExperimentSubset package enables users to perform flexible subsetting of Single-Cell data that comes from the same experiment as well as the consequent storage of these subsets back into the same object. In general, it offers the same interface to the users as the any of the input *Experiment object such SummarizedExperiment, RangedSummarizedExperiment and SingleCellExperiment while imparting the additional subsetting features.