enrichR Given a list of genes this function runs the enrichR() to perform Gene enrichment

enrichRSCE(inSCE, glist, db = NULL)

Arguments

inSCE

Input SingleCellExperiment object.

glist

selected genes for enrichment analysis using enrichR(). Required

db

selected database name from the enrichR database list. if NULL then enrichR will be run on all the available databases on the enrichR database.

Value

enrichRSCE(): returns a data.frame of enrichment terms overlapping in the respective databases along with p-values, z-scores etc.,

Examples

data("mouseBrainSubsetSCE")
enrichRSCE(mouseBrainSubsetSCE, "Cmtm5", "GO_Cellular_Component_2017")
#> Uploading data to Enrichr... Done.
#>   Querying GO_Cellular_Component_2017... Done.
#> Parsing results... Done.
#>            Database_selected                                        Term
#> 1 GO_Cellular_Component_2017 integral component of membrane (GO:0016021)
#>   Overlap   P.value Adjusted.P.value Old.P.value Old.Adjusted.P.value
#> 1   1/842 0.0420998        0.0420998           0                    0
#>   Odds.Ratio Combined.Score Genes                         link
#> 1      19158       60687.03 CMTM5 http://www.geneontology.org/